Arrange the following steps of gene therapy for Adenosine deaminase deficiency in sequence.
(A) Patients lymphocytes are grown in culture outside the body
(B) Functional ADA cDNA is introduced into lymphocytes using retroviral vector (C) Lymphocytes are taken from the blood of the patient
(D) Genetically engineered lymphocytes introduced back to the patient body
Choose the correct answer from the options given below :
(
This question was previously asked in
Shift 09/06/2023 3:30 PM - 6:30 PM
A
(A), (B), (D), (C)
B
(B), (A), (C), (D)
C
(C), (A), (B), (D)
D
(D), (C), (B), (A)
Correct Answer
(C), (A), (B), (D)
Detailed Explanation
Explanation:
The correct sequence for gene therapy in ADA deficiency is:
Lymphocytes are taken from the blood of the patient (C).
Patients' lymphocytes are grown in culture outside the body (A) (to amplify cell numbers).
Functional ADA cDNA is introduced into lymphocytes using a retroviral vector (B).
Genetically engineered lymphocytes are introduced back into the patient's body (D).
Correct Sequence:
(C) → (A) → (B) → (D)
Option (3) matches this order.
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